The Newborn Weeks
The Pulse Oximetry Check Before A Newborn Goes Home
A painless sensor clipped to a newborn's hand and foot screens for certain serious heart defects by comparing oxygen levels above and below a specific point in the circulation.

Among the screens performed before an American newborn leaves the hospital is one that involves no needle at all. It looks trivial and rests on a precise piece of anatomy.
Fetal circulation leaves a connection behind
Before birth, blood largely bypasses the lungs through a vessel connecting the two main outflow arteries, since oxygen arrives through the placenta instead.
That connection normally closes over the first days of life as circulation reorganizes for breathing air.
Certain serious heart defects are partly compensated while the connection remains open, which means an affected newborn can look well during exactly the period when they are in hospital.
Two sensor sites answer one question
The screen measures oxygen saturation at the right hand and at a foot, because those two sites are supplied from different points relative to the connecting vessel.
A meaningful difference between the two readings, or a low reading at either, suggests blood is mixing in a way that ordinary circulation would not produce.
The comparison is what makes the test informative. A single reading would miss the pattern that distinguishes these defects from ordinary variation.
Timing avoids the transition period
Saturation in a newborn changes during the first hours as the lungs take over, so a screen performed too early produces readings that reflect normal transition rather than a defect.
Screening protocols therefore specify a window after birth, and they include a repeat procedure for borderline results rather than treating the first pass as final.
Movement, cold hands and poor sensor contact all affect readings, which is another reason the protocol allows for repeating rather than acting immediately.
A failed screen leads to imaging
The screen does not identify which defect is present, or whether one is. A result outside the criteria leads to evaluation, typically including an echocardiogram.
Some infants who fail have no heart defect at all and are found to have another explanation, including lung conditions or infection, which the evaluation identifies.
Because the consequence of missing these conditions is severe and can develop rapidly at home, the screen is set to refer readily rather than to be specific.
It is a screen, not a guarantee
Some heart defects do not produce the oxygen pattern this screen looks for, and a normal result does not exclude congenital heart disease.
Prenatal ultrasound, newborn examination and later pediatric visits all contribute to detection, and the screen was added to that set rather than replacing any of it.
Any concern about a baby's breathing, color, feeding or alertness after discharge is a reason for prompt medical assessment regardless of what the screen showed.
Questions readers ask
When will my baby get into a routine?
The range is wide enough that no useful average exists. Some settle into a rough pattern within a couple of months, others take considerably longer, and both are ordinary.
Should I wake a newborn to keep to a schedule?
Whether and when to wake a baby for feeds is a clinical question that depends on the individual baby. Ask your midwife or health visitor rather than following a general rule.
Also by Ekta Ranjan
- Newborns make far more noise asleep than anyone tells youThe Newborn Weeks
- Who checks on a newborn in the early weeks, and what they are looking atThe Newborn Weeks
- Skin-to-skin costs nothing and is the least complicated thing in the dayThe Newborn Weeks
- Partners get a smaller share of everything, including the supportLooking After Parents





